Article
Generalized linear model for mapping discrete trait loci implemented with LASSO algorithm.
PloS one - 1 Jan 2014
Xing Jun, Gao Huijiang, Wu Yang, Wu Yani, Li Hongwang, Yang Runqing
Abstract excerpt
Generalized estimating equation (GEE) algorithm under a heterogeneous residual variance model is an extension of the iteratively reweighted least squares (IRLS) method for continuous traits to discrete traits. In contrast to mixture model-based expectation-maximization (EM) algorithm, the GEE algorithm can well detect quantitative trait locus (QTL), especially large effect QTLs located in large marker intervals...
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