Article
Cation-exchange HPLC evaluated for presumptive identification of hemoglobin variants
1997-01-01
Abstract excerpt
Abstract A battery of relatively simple tests allows the presumptive identification of hemoglobin (Hb) variants, making unnecessary structural analysis by protein chemistry methods or DNA sequencing. The primary step in this strategy involves the use of a matrix of electrophoretic mobilities obtained under various experimental conditions. This leads to an unambiguous result in ∼90% of the cases. Additional tests a...
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Identifiers and source
- Literature Corpus work
- 9db87cab-85a1-52ae-8d5a-4e3f46d93d85
- DOI
- 10.1093/clinchem/43.1.34