Article
A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: an application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study.
Diabetes technology & therapeutics - 1 Oct 2007
Kiviniemi Minna, Hermann Robert, Nurmi Jussi, Ziegler Anette G, Knip Mikael, Simell Olli, Veijola Riitta, Lövgren Timo, Ilonen Jorma
Abstract excerpt
BACKGROUND: In the TEDDY (The Environmental Determinants of Diabetes in the Young) study patient eligibility is based on the presence of some selected type 1 diabetes risk-associated human leukocyte antigen DR-DQ genotypes. A practical screening strategy was needed with efficient exclusion of ineligible patients at an early stage. Also, a simple, low-cost, and fast screening system was essential for the primary...
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