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Article

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial.

Annals of the New York Academy of Sciences - 1 Oct 2006

Hagopian William A, Lernmark Ake, Rewers Marian J, Simell Olli G, She Jin-Xiong, Ziegler Anette G, Krischer Jeffrey P, Akolkar Beena

Abstract excerpt

The aim of the TEDDY study is to identify infectious agents, dietary factors, or other environmental agents, including psychosocial factors, which may either trigger islet autoimmunity, type 1 diabetes mellitus (T1DM), or both. The study has two end points: (a) appearance of islet autoantibodies and (b) clinical diagnosis of T1DM. Six clinical centers screen newborns for high-risk HLA genotypes. As of December...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17130573
DOI: 10.1196/annals.1375.049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial.PMID 17130573Read ↗

The Environmental Determinants of Diabetes in the Young (TEDDY) Study.Semantic proximity Read ↗

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.Semantic proximity Read ↗

The environment and the origins of islet autoimmunity and Type 1 diabetes.Semantic proximity Read ↗

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Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.Semantic proximity Read ↗

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study.Semantic proximity Read ↗

Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information.Semantic proximity Read ↗

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.Semantic proximity Read ↗

Environmental trigger(s) of type 1 diabetes: why so difficult to identify?Semantic proximity Read ↗

Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes.Semantic proximity Read ↗

Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.Semantic proximity Read ↗

Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes.Semantic proximity Read ↗

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