Article
Screening for the IDDM high-risk genotype. A rapid microtitre plate method using serum as source of DNA.
Tissue antigens - 1 Oct 2000
Cinek O, Wilkinson E, Paltiel L, Saugstad O D, Magnus P, Rønningen K S
Abstract excerpt
Norwegian babies born with the HLA-DRB1*0401-DQA1*03-DQB1*0302/DRB1*03-DQA1+ ++*05-DQB1*0201 genotype have an estimated 17% lifetime risk of developing insulin-dependent diabetes mellitus (IDDM). Identifying these children is important for future prevention, and for studies of the non-genetic fac...
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