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Article

Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening.

Diabetes - 1 Nov 2008

Barker Jennifer M, Triolo Taylor M, Aly Theresa A, Baschal Erin E, Babu Sunanda R, Kretowski Adam, Rewers Marian J, Eisenbarth George S

Abstract excerpt

OBJECTIVE: People with the HLA genotype DRB1*0301-DQA1*0501-DQB1*0201/DRB1*04-DQA1*0301-DQB1*0302 (DR3/4-DQ8) are at the highest risk of developing type 1 diabetes. We sought to find an inexpensive, rapid test to identify DR3/4-DQ8 subjects using two single nucleotide polymorphisms (SNPs). RESEAR...

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Share to Diabetes Mellitus, Type 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 18694972
DOI: 10.2337/db08-0605
PMCID: PMC2570414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18694972-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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