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Article

Interferon Alfa Regulated Gene Expression in Patients Initiating Interferon Treatment for Chronic Hepatitis C

1 Mar 2003

Abstract excerpt

Interferon alfa (IFN-alpha) is an approved therapeutic agent for chronic hepatitis C. To directly characterize the effects of IFN-alpha in humans, we used microarrays to profile gene expression in peripheral blood mononuclear cells (PBMCs) from hepatitis C patients treated with IFN-alpha. Seven patients were studied using two strategies: (1) in vivo: PBMCs were collected immediately before the first dose of...

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Identifiers

PMID: 12601359
DOI: 10.1053/jhep.2003.50105

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Source receipt: pubmed, retrieved 7 Sept 2026.

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