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Article

Hedgehog signaling pathway and gastric cancer

1 Oct 2005

Abstract excerpt

Hedgehog, WNT, FGF and BMP signaling pathways network together during embryogenesis, tissue regeneration, and carcinogenesis. Aberrant activation of Hedgehog signaling pathway leads to pathological consequences in a variety of human tumors, such as gastric cancer and pancreatic cancer. Endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), surgical gastrectomy and chemotherapy are therapeutic...

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PMID: 16258256
DOI: 10.4161/cbt.4.10.2184

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