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Article

Hedgehog signals regulate multiple aspects of gastrointestinal development

15 Jun 2000

Abstract excerpt

The gastrointestinal tract develops from the embryonic gut, which is composed of an endodermally derived epithelium surrounded by cells of mesodermal origin. Cell signaling between these two tissue layers appears to play a critical role in coordinating patterning and organogenesis of the gut and its derivatives. We have assessed the function of Sonic hedgehog and Indian hedgehog genes, which encode members of the...

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Share to Congenital gastrointestinal and neural anomalies
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PMID: 10821773
DOI: 10.1242/dev.127.12.2763

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