Article
Clinical aspects of disrupted Hedgehog signaling (Review).
International journal of molecular medicine - 1 Oct 2001
Oldak M, Grzela T, Lazarczyk M, Malejczyk J, Skopinski P
Abstract excerpt
The Hedgehog (HH) signaling pathway is involved in patterning and development of a variety of organ systems, including the nervous system, the skeletal system, the craniofacial structures, and the gastrointestinal tract. Recent evidence also implicates this signaling pathway in the postembryonic regulation of stem-cell number in epithelia and blood. The family of HH proteins consists of at least three different...
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