Article
Toll-like receptor 4 (TLR4) gene polymorphisms in celiac disease.
Tissue antigens - 1 Dec 2007
Santin I, Castellanos-Rubio A, Hualde I, Castaño L, Vitoria J C, Bilbao J R
Abstract excerpt
Toll-like receptors (TLRs) participate in the first line of immune defense through antigen pattern recognition, and ligands include exogenous and host-derived molecules. Coding variants in TLR4 have been associated with autoimmune diseases like ulcerative colitis, Crohn's disease, and rheumatoid arthritis. Our aim was to determine whether these polymorphisms are associated with celiac disease (CD). Two coding...
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