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[Association of Toll-like receptor gene with Crohn's disease in Koreans].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Dec 2009

Ye Byong Duk, Yang Suk-Kyun, Song Kyuyoung, Yang Dong-Hoon, Yoon Soon Man, Kim Kyung Jo, Byeon Jeong-Sik, Myung Seung-Jae, Kim Jin-Ho

Abstract excerpt

BACKGROUND/AIMS: Toll-like receptors (TLRs) serve as pattern recognition receptors that recognize specific molecular patterns of pathogens and can mediate the production of proinflammatory cytokines. Recently, TLRs have been identified as susceptibility genes for Crohn's disease (CD) in several studies from Western populations. We investigated the association of genetic variations in TLR4 and TLR9 with CD in...

Topics

Adolescent
Adult
Alleles
Asian People
Crohn Disease
Female
Genetic Predisposition to Disease
Genotype
Humans
Male
Republic of Korea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Toll-Like Receptor 4

Toll-Like Receptor 9

Source

Identifiers

PMID: 20026892
DOI: 10.4166/kjg.2009.54.6.377

Genes

TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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