Article
[Association of Toll-like receptor gene with Crohn's disease in Koreans].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Dec 2009
Ye Byong Duk, Yang Suk-Kyun, Song Kyuyoung, Yang Dong-Hoon, Yoon Soon Man, Kim Kyung Jo, Byeon Jeong-Sik, Myung Seung-Jae, Kim Jin-Ho
Abstract excerpt
BACKGROUND/AIMS: Toll-like receptors (TLRs) serve as pattern recognition receptors that recognize specific molecular patterns of pathogens and can mediate the production of proinflammatory cytokines. Recently, TLRs have been identified as susceptibility genes for Crohn's disease (CD) in several studies from Western populations. We investigated the association of genetic variations in TLR4 and TLR9 with CD in...
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