Article
Associations of non-HLA gene polymorphisms with celiac disease in India.
Scientific reports - 25 Mar 2026
Ramakrishna Balakrishnan S, Singh Alka, Srinivasan Pugazhendhi, Venugopal Giriprasad, Gayathri R, Ahmed Anam, Singh Nidhi, Dutta Sangitanjan, Ahuja Vineet, Makharia Govind K
Abstract excerpt
Celiac disease (CD) is highly prevalent in the wheat eating population of India. While HLA-DQ genotype is the strongest genetic determinant of CD, other genetic factors are likely contribute to genesis of CD. In this case-control study, we determined the frequencies of single nucleotide polymorphisms (SNP) in non-HLA candidate genes that influence the development of CD. DNA obtained from peripheral blood of 376...
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