Article
Effect of angiotensin-converting enzyme insertion/deletion genotype on collagen type I synthesis and degradation in patients with atrial fibrillation and arterial hypertension.
Expert opinion on pharmacotherapy - 1 Oct 2007
Tziakas Dimitrios N, Chalikias Georgios K, Stakos Dimitrios A, Papazoglou Dimitrios, Papanas Nikolaos, Papatheodorou Konstantinos, Chatzikyriakou Sofia V, Kotsiou Stamatia, Maltezos Efstratios, Boudoulas Harisios
Abstract excerpt
OBJECTIVE: The present study was undertaken to assess the impact of the angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) polymorphisms on circulating markers of collagen type I synthesis and degradation, and also to study the effect of therapy with ACE inhibitors on these markers in hypertensive patients with atrial fibrillation (AF). RESEARCH DESIGN AND METHODS: ACE I/D genotypes were assessed in...
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