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Article

Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population.

Pharmacogenetics and genomics - 1 Jun 2008

Ravn Lasse S, Benn Marianne, Nordestgaard Børge G, Sethi Amar A, Agerholm-Larsen Birgit, Jensen Gorm B, Tybjaerg-Hansen Anne

Abstract excerpt

OBJECTIVES: The renin-angiotensin system may play a role in the pathogenesis of atrial fibrillation, and renin-angiotensin system blockers reduce the risk of atrial fibrillation. We hypothesized that polymorphisms in the angiotensinogen and angiotensin-converting enzyme (ACE) genes encoding proteins in this system predict risk of atrial fibrillation. METHODS AND RESULTS: We genotyped 9235 individuals from the...

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Source

Identifiers

PMID: 18496132
DOI: 10.1097/FPC.0b013e3282fce3bd

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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