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Article

Functional polymorphisms in ACE and CYP11B2 genes and atrial fibrillation in patients with hypertensive heart disease.

Clinical chemistry and laboratory medicine - 1 Jan 2009

Huang Mingfang, Gai Xiaobo, Yang Xiangyue, Hou Jianping, Lan Xiaopeng, Zheng Weixing, Chen Fengping, He Jiake

Abstract excerpt

BACKGROUND: The activated renin-angiotensin-aldosterone system has been reported to play an important role in the pathogenesis of atrial fibrillation (AF). We hypothesized that functional genetic variations of angiotensin-converting enzyme (ACE) and CYP11B2 genes may influence the susceptibility to AF in patients with hypertensive heart disease. METHODS: The I/D polymorphism of ACE was detected by polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP11B2

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Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 19117407
DOI: 10.1515/CCLM.2009.023

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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