Article
Angiotensin-converting enzyme-gene polymorphism is associated with collagen I synthesis and QT dispersion in essential hypertension.
Journal of hypertension - 1 May 2003
Takahashi Toru, Ueno Hitoshi, Yasumoto Kotaro, Kagitani Satoshi, Tomoda Fumihiro, Inoue Hiroshi, Takata Masanobu
Abstract excerpt
AIM: This study tested the hypothesis that abnormal QT dispersion, an indicator of arrhythmogenic risk, is associated with angiotensin-converting enzyme (ACE) gene polymorphism and abnormalities of collagen metabolism. METHODS: A total of 132 patients with untreated essential hypertension (EHT) were recruited. QT dispersion corrected by heart rate (QTc) on a 12-lead electrocardiogram, ACE genotype, left...
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