Article
Novel methods for detecting epistasis in pharmacogenomics studies.
Pharmacogenomics - 1 Sept 2007
Motsinger Alison A, Ritchie Marylyn D, Reif David M
Abstract excerpt
The importance of gene-gene and gene-environment interactions in the underlying genetic architecture of common, complex phenotypes is gaining wide recognition in the field of pharmacogenomics. In epidemiological approaches to mapping genetic variants that predict drug response, it is important that researchers investigate potential epistatic interactions. In the current review, we discuss data-mining tools...
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