Article
Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes.
The pharmacogenomics journal - 1 Jun 2008
Tolstrup Janne Schurmann, Nordestgaard Børge Grønne, Rasmussen Søren, Tybjaerg-Hansen Anne, Grønbaek Morten
Abstract excerpt
Alcohol drinking habits and alcoholism are partly genetically determined. Alcohol is degraded primarily by alcohol dehydrogenase (ADH) wherein genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. It is biologically plausible that these variations may be associated with alcohol drinking habits and alcoholism. By genotyping 9080 white men and women from the general population,...
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