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Article

Major genetic components underlying alcoholism in Korean population.

Human molecular genetics - 15 Mar 2008

Kim Dai-Jin, Choi Ihn-Geun, Park Byung Lae, Lee Boung-Chul, Ham Byung-Joo, Yoon Sujung, Bae Joon Seol, Cheong Hyun Sub, Shin Hyoung Doo

Abstract excerpt

Alcohol metabolism is one of the biological determinants that could significantly be influenced by genetic polymorphisms in alcohol-metabolism genes. Alcohol dehydrogenase (ADH) converts alcohol to acetaldehyde, and aldehyde dehydrogenase (ALDH) converts acetaldehyde to acetate. The well-known genetic polymorphisms in ADH1B(His47Arg) and ALDH2(Glu487Lys) have dramatic effects on the rate of metabolizing alcohol...

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Source

Identifiers

PMID: 18056758
DOI: 10.1093/hmg/ddm357

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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