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Article

Biology, Genetics, and Environment: Underlying Factors Influencing Alcohol Metabolism.

Alcohol research : current reviews - 1 Jan 2016

Wall Tamara L, Luczak Susan E, Hiller-Sturmhöfel Susanne

Abstract excerpt

Gene variants encoding several of the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest genetic associations with risk for alcohol dependence. Certain genetic variants (i.e., alleles)--particularly the ADH1B*2, ADH1B*3, ADH1C*1, and ALDH2*2 alleles--have been associated with lower rates of alcohol dependence. These alleles may lead to an...

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Source

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Identifiers

PMID: 27163368
PMCID: PMC4872614

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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