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Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review

15 Oct 2018

Abstract excerpt

Alcohol use disorders (AUDs) are complex traits, meaning that variations in many genes contribute to the risk, as does the environment. Although the total genetic contribution to risk is substantial, most individual variations make only very small contributions. By far the strongest contributors are functional variations in 2 genes involved in alcohol (ethanol [EtOH]) metabolism. A functional variant in alcohol...

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Alcohol Consumption and Health Effects
Liver Disease Diagnosis and Treatment
Peroxisome Proliferator-Activated Receptors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30320893
DOI: 10.1111/acer.13904

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