Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological characteristics of colorectal cancer with family history: an evaluation of family history as a predictive factor for microsatellite instability.

Journal of Korean medical science - 1 Sept 2007

Park In Ja, Kim Hee Cheol, Yoon Yong Sik, Yu Chang Sik, Jang Se Jin, Kim Jin Cheon

Abstract excerpt

To determine whether family history of cancer may be a risk factor for the mutator phenotype in colorectal cancer, we recruited 143 consecutive colorectal cancer patients with a family history of accompanying cancers not meeting the Amsterdam criteria. Microsatellite instability (MSI) at 5 markers, hMLH1-promoter methylation, and expression of mismatch repair (MMR) proteins (hMLH1, hMSH2, hMSH6, hMPS1, and hPMS2)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to DNA Mismatch Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

Share to Microsatellite Instability

Share to Mismatch Repair Endonuclease PMS2

Share to MutL Protein Homolog 1

Share to MutL Proteins

Share to MutS Homolog 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 17923762
DOI: 10.3346/jkms.2007.22.S.S91
PMCID: PMC2694396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological characteristics of colorectal cancer with family history: an evaluation of family history as a predictive factor for microsatellite instability.PMID 17923762Read ↗

Characterization of mutator phenotype in familial colorectal cancer patients not fulfilling amsterdam criteria.Semantic proximity Read ↗

The association of tumor microsatellite instability phenotype with family history of colorectal cancer.Semantic proximity Read ↗

Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer.Semantic proximity Read ↗

Clinical significance of microsatellite instability in colorectal cancer.Semantic proximity Read ↗

Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.Semantic proximity Read ↗

Implications of Familial Colorectal Cancer Risk Profiles and Microsatellite Instability StatusSemantic proximity Read ↗

Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair.Semantic proximity Read ↗

Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.Semantic proximity Read ↗

Increased cancer predisposition in family members of colorectal cancer patients harboring the p.V600E BRAF mutation: a population-based study.Semantic proximity Read ↗

Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma.Semantic proximity Read ↗

Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study.Semantic proximity Read ↗

Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.