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Article

Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2005

Llor Xavier, Pons Elisenda, Xicola Rosa M, Castells Antoni, Alenda Cristina, Piñol Virgínia, Andreu Montserrat, Castellví-Bel Sergi, Payá Artemio, Jover Rodrigo, Bessa Xavier, Girós Anna, Roca Anna, Gassull Miquel A

Abstract excerpt

PURPOSE: Hereditary nonpolyposis colorectal cancer (HNPCC) is the commonest form of inherited colorectal cancer. Whereas it has been known that mismatch repair gene mutations are the underlying cause of HNPCC, an undetermined number of patients do not have these alterations. The main objectives of this study were to assess the relevance of clinically defined HNPCC patients without characteristic mutator pathway...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16243801
DOI: 10.1158/1078-0432.CCR-05-0965

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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