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Article

S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon Ty1.

Molecular and cellular biology - 1 Dec 2007

Curcio M Joan, Kenny Alison E, Moore Sharon, Garfinkel David J, Weintraub Matthew, Gamache Eric R, Scholes Derek T

Abstract excerpt

The mobility of the Ty1 retrotransposon in the yeast Saccharomyces cerevisiae is restricted by a large collection of proteins that preserve the integrity of the genome during replication. Several of these repressors of Ty1 transposition (Rtt)/genome caretakers are orthologs of mammalian retroviral restriction factors. In rtt/genome caretaker mutants, levels of Ty1 cDNA and mobility are increased; however, the...

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Identifiers

PMID: 17923678
DOI: 10.1128/MCB.01095-07
PMCID: PMC2169403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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