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Article

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.

The Journal of biological chemistry - 18 Nov 2005

Sabbioneda Simone, Minesinger Brenda K, Giannattasio Michele, Plevani Paolo, Muzi-Falconi Marco, Jinks-Robertson Sue

Abstract excerpt

The use of translesion synthesis (TLS) polymerases to bypass DNA lesions during replication constitutes an important mechanism to restart blocked/stalled DNA replication forks. Because TLS polymerases generally have low fidelity on undamaged DNA, the cell must regulate the interaction of TLS polymerases with damaged versus undamaged DNA to maintain genome integrity. The Saccharomyces cerevisiae checkpoint...

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PMID: 16169844
DOI: 10.1074/jbc.M507638200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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