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Article

Predicting the rate of cognitive decline in aging and early Alzheimer disease.

Neurology - 13 Jul 2004

Adak S, Illouz K, Gorman W, Tandon R, Zimmerman E A, Guariglia R, Moore M M, Kaye J A

Abstract excerpt

OBJECTIVES: To determine prognostic factors affecting the course of Alzheimer disease (AD) and to determine the role of region-specific brain volumes as predictors of cognitive decline. METHODS: Longitudinal data from 166 normal elderly individuals and 59 early AD patients were analyzed. Brain volumes were extracted from MRI scans using semiautomated recursive segmentation methods. Prognostic factors were...

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PMID: 15249619
DOI: 10.1212/01.wnl.0000132520.69612.ab

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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