Article
Association analysis between K and -116A variants of butyrylcholinesterase and Alzheimer's disease in a Brazilian population.
Chemico-biological interactions - 25 Mar 2013
Simão-Silva Daiane Priscila, Bertolucci Paulo Henrique Ferreira, de Labio Roger William, Payão Spencer Luiz Marques, Furtado-Alle Lupe, Souza Ricardo Lehtonen Rodrigues
Abstract excerpt
In Alzheimer's disease (AD) a reduction in acetylcholinesterase (AChE) and an increase in butyrylcholinesterase (BChE) activity are observed. K variant (539T) is the most common variant of the BCHE gene and, although controversial, several studies reported association between K variant and AD. Pr...
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