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Article

Nucleolar localization of parafibromin is mediated by three nucleolar localization signals.

FEBS letters - 30 Oct 2007

Hahn Michael A, Marsh Deborah J

Abstract excerpt

Parafibromin is a putative tumor suppressor encoded by HRPT2 and implicated in parathyroid tumorigenesis. We previously reported a functional bipartite nuclear localization signal (NLS) at residues 125-139. We now demonstrate that parafibromin exhibits nucleolar localization, mediated by three nucleolar localization signals (NoLS) at resides 76-92, 192-194 and 393-409. These NoLS represent clusters of basic amino...

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Identifiers

PMID: 17923126
DOI: 10.1016/j.febslet.2007.09.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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