Article
Parafibromin--functional insights.
Journal of internal medicine - 1 Jul 2009
Newey P J, Bowl M R, Thakker R V
Abstract excerpt
Parafibromin is a predominantly nuclear protein with a tumour suppressor role in the development of hereditary and nonhereditary parathyroid carcinomas, and the hyperparathyroidism-jaw tumour syndrome, which is associated with renal and uterine tumours. Parafibromin is a component of the highly conserved PAF1 complex, which regulates transcriptional events and histone modifications. The parafibromin/PAF1 complex...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
