Article
Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice.
PLoS pathogens - 5 Oct 2007
Hatta Masato, Hatta Yasuko, Kim Jin Hyun, Watanabe Shinji, Shinya Kyoko, Nguyen Tung, Lien Phuong Song, Le Quynh Mai, Kawaoka Yoshihiro
Abstract excerpt
Highly pathogenic avian H5N1 influenza A viruses have spread throughout Asia, Europe, and Africa, raising serious worldwide concern about their pandemic potential. Although more than 250 people have been infected with these viruses, with a consequent high rate of mortality, the molecular mechanisms responsible for the efficient transmission of H5N1 viruses among humans remain elusive. We used a mouse model to...
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