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Article

PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice.

Journal of virology - 1 Jan 2011

Zhou Bin, Li Yan, Halpin Rebecca, Hine Erin, Spiro David J, Wentworth David E

Abstract excerpt

Influenza A viruses are human and animal pathogens that cause morbidity and mortality, which range from mild to severe. The 2009 H1N1 pandemic was caused by the emergence of a reassortant H1N1 subtype (H1N1pdm) influenza A virus containing gene segments that originally circulated in human, avian, and swine virus reservoirs. The molecular determinants of replication and pathogenesis of H1N1pdm viruses in humans...

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Source

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Identifiers

PMID: 20962098
DOI: 10.1128/JVI.01694-10
PMCID: PMC3014153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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