Article
Peptide YY regulates bone turnover in rodents.
Gastroenterology - 1 Nov 2007
Wortley Katherine E, Garcia Karen, Okamoto Haruka, Thabet Karen, Anderson Keith D, Shen Victor, Herman Jim P, Valenzuela David, Yancopoulos George D, Tschöp Matthias H, Murphy Andrew, Sleeman Mark W
Abstract excerpt
BACKGROUND & AIMS: Peptide YY (PYY) and pancreatic polypeptide (PPY) are members of the neuropeptide Y peptide family. The neuropeptide Y receptor signaling pathway has been implicated in a number of physiologic processes, including the regulation of energy balance and bone mass. To investigate the contribution of endogenous PYY and PPY to these processes, we generated both Pyy- and Ppy-deficient mice. METHODS:...
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