Article
A PYY Q62P variant linked to human obesity.
Human molecular genetics - 1 Feb 2006
Ahituv Nadav, Kavaslar Nihan, Schackwitz Wendy, Ustaszewska Anna, Collier John Michael, Hébert Sybil, Doelle Heather, Dent Robert, Pennacchio Len A, McPherson Ruth
Abstract excerpt
Peptide YY (PYY) has been implicated in the control of food intake through functional studies in rodents and humans. To investigate whether genetic alterations within this gene result in abnormal weight in humans, we sequenced its coding exons and splice sites in a large cohort of extremely obese...
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