Article
carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA-binding protein identical to XerB and PepA, also required for resolution of ColEI multimers.
Journal of molecular biology - 21 Jul 1995
Charlier D, Hassanzadeh G, Kholti A, Gigot D, Piérard A, Glansdorff N
Abstract excerpt
The carP gene involved in pyrimidine-specific regulation of the upstream P1 promoter of the Escherichia coli carAB operon has been cloned in vivo on a mini-Mu replicon, sequenced and shown to be identical to the xerB (pepA) gene encoding aminopeptidase A, a protein also involved in the Xer-mediated site-specific recombination at ColEI cer. The trans-dominant allele carP6 was cloned as well and shown to bear a...
Topics
- Amino Acid Sequence
- Aminopeptidases
- Bacterial Proteins
- Bacteriocin Plasmids
- Base Sequence
- Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
- Chromosome Mapping
- Cloning, Molecular
- DNA Nucleotidyltransferases