Article
The iscS gene deficiency affects the expression of pyrimidine metabolism genes.
Biochemical and biophysical research communications - 1 Aug 2008
Mihara Hisaaki, Hidese Ryota, Yamane Masahiro, Kurihara Tatsuo, Esaki Nobuyoshi
Abstract excerpt
Inactivation of iscS encoding cysteine desulfurase results in a slow growth phenotype associated with the deficiency of iron-sulfur clusters, thiamine, NAD, and tRNA thionucleosides in Escherichia coli. However, the other roles of iscSin vivo are unknown. By using differential screening strategie...
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