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Article

The A y allele at the agouti locus enhances sensitivity to endotoxin-induced lethality in mice.

The Journal of veterinary medical science - 1 Sept 2007

Suto Jun-ichi

Abstract excerpt

In the course of investigations on anorexia during infection, I found that B6-A(y) mice had significantly increased sensitivity to lipopolysaccharide (LPS)-induced lethality as compared with isogenic B6 mice. I also found that the sensitivity to the lethal effect of LPS dramatically increased in aged mice (age effect), both B6 and B6-A(y). However, the A(y) effect of enhancing sensitivity to LPS-induced lethality...

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Identifiers

PMID: 17917378
DOI: 10.1292/jvms.69.931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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