Article
Cardiovascular and metabolic responses to fasting and thermoneutrality in Ay mice.
Physiology & behavior - 1 Apr 2003
Williams T D, Chambers J B, Gagnon S P, Roberts L M, Henderson R P, Overton J M
Abstract excerpt
Several lines of evidence support a role for reduced melanocortin signaling in the regulation of metabolic rate and cardiovascular function during negative energy balance. We tested the hypothesis that agouti yellow (B6.Cg-A(y)) mice would exhibit blunted physiologic responses to fasting and thermoneutrality. Male B6.Cg-A(y) mice (A(y); n=11, 34+/-2 g) and lean B6 littermates (B6; n=7, 26+/-2 g) were implanted...
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