Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leptin responsiveness in mice that ectopically express agouti protein.

Physiology & behavior - 1 Jan 2000

Harris Ruth B S, Mitchell Tiffany D, Mynatt Randall L

Abstract excerpt

Agouti protein is an endogenous antagonist of melanocortin receptors (MCR), including MCR3 and MCR4, which have been implicated as part of the hypothalamic mechanism that mediates leptin-induced hypophagia. In this experiment we examined the effects of peripheral and central leptin administration in male and female beta-actin promoter (BAPa) mice that express agouti protein ectopically and have a phenotype that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agouti Signaling Protein
Share to Body Composition
Share to Brain Chemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus

Share to Eating

Share to Injections, Intraventricular

Share to Intercellular Signaling Peptides and Proteins

Share to Leptin

Source

Identifiers

PMID: 11890964
DOI: 10.1016/s0031-9384(01)00653-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leptin responsiveness in mice that ectopically express agouti protein.PMID 11890964Read ↗

The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse modelsSemantic proximity Read ↗

The yellow agouti mutation alters some but not all responses to diet and exercise.Semantic proximity Read ↗

Agouti/melanocortin interactions with leptin pathways in obesity.Semantic proximity Read ↗

Melanocortins and body weight regulation: glucocorticoids, Agouti-related protein and beyond.Semantic proximity Read ↗

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related ProteinSemantic proximity Read ↗

Overexpression of agouti protein and stress responsiveness in mice.Semantic proximity Read ↗

Melanocortin-4 receptor: a novel signalling pathway involved in body weight regulation.Semantic proximity Read ↗

The yellow mouse obesity syndrome and mechanisms of agouti-induced obesity.Semantic proximity Read ↗

Physiological and anatomical circuitry between Agouti-related protein and leptin signaling.Semantic proximity Read ↗

Influence of abnormally high leptin levels during pregnancy on metabolic phenotypes in progeny mice.Semantic proximity Read ↗

Mouse models of obesity.Semantic proximity Read ↗

Pro-opiomelanocortin and weight regulation: from mice to men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.