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Article

Loss-of-function mutations in melanocortin-1 receptor modulate immune response in teleost fishes.

Fish & shellfish immunology - 1 Dec 2022

Fierro-Castro Camino, Rotllant Josep, Cerdá-Reverter Jose Miguel, Tort Lluís

Abstract excerpt

The melanocortin system is an ancient neuroendocrine system conserved from teleosts to mammals. The melanocortin system is a set of complex neuroendocrine signaling pathways involved in numerous physiological processes, and particularly associated with the hypothalamic-pituitary-interrenal (HPI) axis response. The melanocortin 1 receptor (MC1R) is the central melanocortin receptor involved in pigmentation in...

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PMID: 36334699
DOI: 10.1016/j.fsi.2022.10.064

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