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Article

Fever responses of Zucker rats with and without fatty mutation of the leptin receptor.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jan 2002

Ivanov Andrei I, Romanovsky Andrej A

Abstract excerpt

Leptin is thought to be involved in febrigenic signaling from the periphery to the brain. Zucker obese rats have a so-called fatty mutation in the leptin receptor gene and express a dysfunctional protein. Studies comparing the fever responses of fatty (fa/fa) rats and of their lean (Fa/Fa and Fa/fa) counterparts yield contradictory results. To resolve these contradictions, we evaluated the effect of fatty...

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Source

Identifiers

PMID: 11742853
DOI: 10.1152/ajpregu.00376.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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