Article
Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli.
The EMBO journal - 31 Oct 2007
Fossum Solveig, Crooke Elliott, Skarstad Kirsten
Abstract excerpt
The replication period of Escherichia coli cells grown in rich medium lasts longer than one generation. Initiation thus occurs in the 'mother-' or 'grandmother generation'. Sister origins in such cells were found to be colocalized for an entire generation or more, whereas sister origins in slow-growing cells were colocalized for about 0.1-0.2 generations. The role of origin inactivation (sequestration) by the...
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