Article
[DNA repair--a fundamental factor in ageing and development of cancer].
Ugeskrift for laeger - 12 Jun 2006
Rasmussen Lene Juel, Stevnsner Tinna, Bohr Vilhelm A
Abstract excerpt
Advanced age and increased incidence of many illnesses such as cancer are closely linked. The reasons for such a link are numerous but one important factor is DNA repair. DNA repair pathways in both nuclei and mitochondria ensure that genomic instability is minimised, thus preventing transformation and premature cellular decay. However, overall cellular DNA repair capacity decreases with age; moreover, some...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
