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Article

DNA Damage and Repair: From Molecular Mechanisms to Health Implications

20 Jan 2008

Abstract excerpt

DNA is subjected to several modifications, resulting from endogenous and exogenous sources. The cell has developed a network of complementary DNA-repair mechanisms, and in the human genome, >130 genes have been found to be involved. Knowledge about the basic mechanisms for DNA repair has revealed an unexpected complexity, with overlapping specificity within the same pathway, as well as extensive functional...

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PMID: 18205545
DOI: 10.1089/ars.2007.1830

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