Article
Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis.
Journal of molecular medicine (Berlin, Germany) - 1 Oct 2005
Booth D R, Arthur A T, Teutsch S M, Bye C, Rubio J, Armati P J, Pollard J D, Heard R N S, Stewart G J
Abstract excerpt
Multiple sclerosis (MS) is an enigmatic disease of the central nervous system resulting in sclerotic plaques with the pathological hallmarks of demyelination and axonal damage, which can be directly or indirectly orchestrated by cells from the peripheral circulation. The majority of patients with MS follow a relapsing-remitting course in the early stages of the disease (RRMS) but most ultimately enter a secondary...
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