Article
Functional roles of Otx2 transcription factor in postnatal mouse retinal development.
Molecular and cellular biology - 1 Dec 2007
Koike Chieko, Nishida Akihiro, Ueno Shinji, Saito Hiromitsu, Sanuki Rikako, Sato Shigeru, Furukawa Akiko, Aizawa Shinichi, Matsuo Isao, Suzuki Noboru, Kondo Mineo, Furukawa Takahisa
Abstract excerpt
We previously reported that Otx2 is essential for photoreceptor cell fate determination; however, the functional role of Otx2 in postnatal retinal development is still unclear although it has been reported to be expressed in retinal bipolar cells and photoreceptors at postnatal stages. In this study, we first examined the roles of Otx2 in the terminal differentiation of photoreceptors by analyzing Otx2; Crx...
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