Article
A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.
BMC developmental biology - 2 Nov 2007
Fossat Nicolas, Le Greneur Coralie, Béby Francis, Vincent Stéphane, Godement Pierre, Chatelain Gilles, Lamonerie Thomas
Abstract excerpt
BACKGROUND: Dynamic monitoring of protein expression and localization is fundamental to the understanding of biological processes. The paired-class homeodomain-containing transcription factor Otx2 is essential for normal head and brain development in vertebrates. Recent conditional knockout studies have pointed to multiple roles of this protein during late development and post-natal life. Yet, later expression...
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