Article
Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina.
Development (Cambridge, England) - 1 Jan 2005
de Melo Jimmy, Du Guoyan, Fonseca Mario, Gillespie Leigh-Anne, Turk William J, Rubenstein John L R, Eisenstat David D
Abstract excerpt
Dlx homeobox genes, the vertebrate homologs of Distal-less, play important roles in the development of the vertebrate forebrain, craniofacial structures and limbs. Members of the Dlx gene family are also expressed in retinal ganglion cells (RGC), amacrine and horizontal cells of the developing and postnatal retina. Expression begins at embryonic day 12.5 and is maintained until late embryogenesis for Dlx1, while...
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