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Article

Differential CRX and OTX2 expression in human retina and retinoblastoma

3 Aug 2009

Abstract excerpt

The histogenesis of retinoblastoma tumors remains controversial, with the cell-of-origin variably proposed to be an uncommitted retinal progenitor cell, a bipotent committed cell, or a cell committed to a specific lineage. Here, we examine the expression of two members of the orthodenticle family implicated in photoreceptor and bipolar cell differentiation, cone-rod homeobox, CRX, and orthodenticle homeobox 2,...

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PMID: 19686387
DOI: 10.1111/j.1471-4159.2009.06322.x

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Differential CRX and OTX2 expression in human retina and retinoblastomaPMID 19686387Read ↗

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