Article
Homology modeling and in silico prediction of Ulcerative colitis associated polymorphisms of NOD1.
Molecular and cellular probes - 1 Oct 2017
Majumdar Ishani, Nagpal Isha, Paul Jaishree
Abstract excerpt
Cytosolic pattern recognition receptors play key roles in innate immune response. Nucleotide binding and oligomerisation domain containing protein 1 (NOD1) belonging to the Nod-like receptor C (NLRC) sub-family of Nod-like receptors (NLRs) is important for detection and clearance of intra-cellular Gram negative bacteria. NOD1 is involved in activation of pro-inflammatory pathways. Limited structural data is...
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